Health Economics & Outcomes Research
- Cost-of-illness studies
- Cost-effectiveness and cost-utility models
- Opportunity and market evaluations for product development and licensing decisions
- Design of economic and outcomes components for clinical trials
- Analysis and modeling of clinical trial data
- Clinical trial outcomes data collection and data management
- Post-Approval/Phase IV Studies
- Budget-impact models
- Patient preference evaluations
- Health-related quality of life (HRQoL) assessments
- Post-marketing safety assessments
- Physician decision-making studies
- Work-site-based studies (productivity and safety)
- Analysis of national survey data (e.g., NAMCS, MEPS)
- Instrument development (focus groups, cognitive debriefing, pilot testing)
- Validation (reliability and validity testing)
- Interpretation (effect size, clinically meaningful difference)
- Meta-analysis
- Systematic review
- Decision analytic models
- Markov models
Clinical Development
- Phase I-IV protocol development - including imaging studies for inhalation products
- Initial dose setting based on preclinical data, indication(s) and delivery system
- Preparation of investigator brochures (IB) and annual IND safety reports
- Preparation of informed consent documents
- Pharmacokinetic, drug-drug interaction and bioequivalence trials
- Clinical Advisory Board selection and moderation
- CRO selection and management
- IRB selection and management Data management
- Drug safety monitoring management
- Statistical analysis
- Clinical study report writing
- Preparation for and representation at FDA/regulatory authority meetings
- Interactions with FDA and other regulatory authorities
- Paper and/or eCTD preparation of regulatory submissions (IND/NDA, CTA/MAA, BLA, ANDA etc)
- Clinical trial submissions and updates to ClinicalTrials.gov
Environmental / Occupational Health & Safety
- Pre-exposure third party risk assessments of facilities, system audits, and efficacy of EHS management systems and practices
- Product containment and facility alarm systems
- Post exposure root cause analysis, containment, decontamination, and clearance
- Education, communication, and assessment of community concerns regarding environmental impacts and worker health and safety issues
- Long-term epidemiological studies
- Management, toxicological assessment, and review of new compounds and intermediates